Abstract

Background: The greater saphenous vein is still frequently used as a conduit for coronary artery bypass grafting (CABG). Previously, veins were harvested through a single continuous skin incision, commonly referred to as open vein harvesting (OVH), while endoscopic vein harvesting (EVH) techniques have become increasingly popular. However, the postoperative consumption of healthcare resources remains uncertain. Therefore, the present study performed a systematic review, with meta-analysis, of outcomes relating to consumption of healthcare resources and clinical effectiveness following EVH and OVH for CABG. Methods: A systematic search was performed in five databases. OVH was defined as the use of open harvesting techniques using a single continuous incision, and all studies comparing EVH to OVH for CABG were eligible. Results: EVH was associated with increased duration of surgery, no difference in the length of stay in intensive care units, a reduced total length of stay in hospital, a reduced need for antibiotic treatment for leg wound infections, a reduced need for follow-up visit(s) at general practitioners/out-patient clinics, a reduced need for visit(s) by the homecare nurses, a reduced need for revision(s) of the leg wound, a reduced need for readmission(s) related to leg wounds complications and no difference in repeat cardiac catheterization(s). Furthermore, EVH reduced pain intensity approximately five days postoperatively, but not 30 days postoperatively. EVH did not increase the occurrence of mid-term myocardial infarction, recurrence of chest pain, repeat revascularization and mid-term allcause mortality. Conclusions: EVH provides safe clinical outcomes compared to OVH while reducing the short-term postoperative resource consumption. This article provides a formal synthesis of the available data on clinical effectiveness and consumption of healthcare resources following EVH and OVH for CABG, hence enabling future investigation of the long-term cost-effectiveness of methods.

Highlights

  • Most patients suffering from multi-vessel coronary artery disease should be treated with coronary artery bypass grafting (CABG) and the use of arterial conduits was increasing, the greater saphenous vein is still frequently used as a conduit [1]

  • The present study performed a systematic review with meta-analysis of outcomes relating to resource consumption and clinical effectiveness following endoscopic vein harvesting (EVH) and open vein harvesting (OVH) with a single continuous skin incision

  • Johnson & Johnson, Somervill, NJ, USA), the Karl Storz Endoskope (Karl Storz, Tuttlingen, Germany), the VirtuoSaph system (Terumo Cardiovascular Corp., Ann Arbor, myocardial infarction (MI), USA), the EndoSaph Vein Harvest system (Unites States Surgical, Tyco Healthcare, Norwalk, CT, USA), a mixture of above mentioned, or if primary author’s stated EVH was used the system was not defined

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Summary

Introduction

Most patients suffering from multi-vessel coronary artery disease should be treated with coronary artery bypass grafting (CABG) and the use of arterial conduits was increasing, the greater saphenous vein is still frequently used as a conduit [1]. The harvesting process involved an open vein harvesting (OVH) technique with a single continuous skin incision but today the majority is harvested using an endoscopic vein harvesting (EVH) technique, as it reduces leg wound morbidity [2,3,4]. Several meta-analyses have been conducted to compare OVH techniques to minimally invasive vein harvesting techniques, yet none have compared OVH using a single continuous skin incision to EVH using total endoscopic equipment [413]. The present study performed a systematic review with meta-analysis of outcomes relating to resource consumption and clinical effectiveness following EVH and OVH with a single continuous skin incision. The present study performed a systematic review, with meta-analysis, of outcomes relating to consumption of healthcare resources and clinical effectiveness following EVH and OVH for CABG

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