Abstract
(Abstracted from J Assist Reprod Genet 2019;36:1649–1656) Although endometriosis affects approximately 10% of women of reproductive age and 40% of infertile women, the physiological mechanism of how this chronic inflammatory disease affects fertility remains unclear. There is little consensus in the literature that IVF/ICSI outcomes are impacted by endometriosis.
Highlights
Endometriosis is a benign but chronic inflammatory disease affecting around 10% of women of reproductive age with a high prevalence of up to 40% in infertile women [1]
Women with endometriosis did not differ in demographic variables including age (p = 0.91) or BMI (p = 0.81) (Table 1), when compared to controls
In women with endometriosis (n = 172), 38.4% had ovarian endometrioma (n = 66); and in 10.5% of cases (n = 18), endometriosis was associated with additional infertility factors
Summary
Endometriosis is a benign but chronic inflammatory disease affecting around 10% of women of reproductive age with a high prevalence of up to 40% in infertile women [1]. J Assist Reprod Genet (2019) 36:1649–1656 similar to those of controls [2] This data is suggesting a detrimental effect of endometriosis only in combination with other infertility diagnoses, such as concomitant male factor infertility, diminished ovarian reserve, or tubal factor infertility. A meta-analysis has indicated a decrease in oocyte yields and reduced clinical pregnancy rate in patients with endometriosis undergoing IVF, compared to controls; multiple embryos had been replaced in most of the studies and the live-birth rate was similar [3, 4]. The effect of age has been difficult to disentangle in previous studies, as even in young women, the bulk of data on IVF/ICSI outcomes in women with endometriosis is based on treatments using multiple embryos for transfer [2, 7,8,9]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
