Abstract
This chapter discusses nine genetic disorders affecting the endocrine and immune systems of the body. These include congenital adrenal hyperplasia, adrenoleukodystrophy, Cockayne syndrome, diastrophic dysplasia, autoimmune polyglandular syndrome, asthma and allergy, severe combined immunodeficiency (SCID), immunodeficiency with hyper-IgM syndromes, and DiGeorge syndrome. The endocrine system made is a complex collection of hormone-producing glands involved in the control of basic body functions such as metabolism, behaviour, growth, and sexual development. The immune system is a complex and highly developed system which protects the body from pathogenic invaders and other foreign molecules or particles like allergens. The body uses three lines of defence against invaders, two of them non-specific and one highly specific. Most immune disorders result from either an excessive immune response or an “autoimmune attack.”
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