Abstract

Introduction:Devices for male circumcision (MC) are becoming available in 14 priority countries where MC is being implemented for HIV prevention. Understanding potential impact on demand for services is one important programmatic consideration because countries determine whether to scale up devices within MC programs.Methods:A population-based survey measuring willingness to undergo MC, assuming availability of surgical MC and 3 devices, was conducted among 1250 uncircumcised men, ages 10–49 years in Zambia and 1000 uncircumcised men, ages 13–49 years in Zimbabwe. Simulated Test Market methodology was used to estimate incremental MC demand and the extent to which devices might be preferred over surgery, assuming availability of: surgical MC in both countries; the devices PrePex, ShangRing, and Unicirc in Zambia; and PrePex in Zimbabwe.Results:Modeled estimates indicate PrePex has the potential to provide an overall increase in MC demand ranging from an estimated 13%–50%, depending on country and WHO prequalification ages, replacing 11%–41% of surgical procedures. In Zambia, ShangRing could provide 8% overall increase, replacing 45% of surgical procedures, and Unicirc could provide 30% overall increase, replacing 85% of surgical procedures.Conclusions:In both countries, devices have potential to increase overall demand for MC, assuming wide scale awareness and availability of circumcision by the devices. With consideration for age and country, PrePex may provide the greatest potential increase in demand, followed by Unicirc (measured in Zambia only) and ShangRing (also Zambia only). These results inform one program dimension for decision making on potential device introduction strategies; however, they must be considered within the broader programmatic context.

Highlights

  • Devices for male circumcision (MC) are becoming available in 14 priority countries where MC is being implemented for HIV prevention

  • Simulated Test Market methodology was used to estimate incremental MC demand and the extent to which devices might be preferred over surgery, assuming availability of: surgical MC in both countries; the devices PrePex, ShangRing, and Unicirc in Zambia; and PrePex in Zimbabwe

  • The study was conceived by S.K.S. and S.K. and designed by S.K., F.F., and INTRODUCTION The efficacy of medical male circumcision (MC) in the reduction of female-to-male HIV transmission has been demonstrated by observational studies and randomized controlled trials, and MC is recommended for HIV prevention in countries with high HIV prevalence and low MC prevalence.[1,2,3,4,5]

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Summary

Introduction

Devices for male circumcision (MC) are becoming available in 14 priority countries where MC is being implemented for HIV prevention. The efficacy of medical male circumcision (MC) in the reduction of female-to-male HIV transmission has been demonstrated by observational studies and randomized controlled trials, and MC is recommended for HIV prevention in countries with high HIV prevalence and low MC prevalence.[1,2,3,4,5] MC programs have been scaling up, the current uptake of MC is too low to reach the goal of 80% MC prevalence within the established time frame. PrePex is an elastic collar compression device, consisting of a rigid inner ring and an elastic outer ring that restrict blood flow resulting in ischemia and necrosis of the foreskin; it does not require a sterile field or injected anesthesia. ShangRing is a collar clamp device, consisting of 2 concentric plastic rings that provide tight compression to achieve hemostasis, at which time the live foreskin tissue is removed.

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