Abstract
Curcumin, a yellow pigment present in turmeric has been shown to exhibit numerous activities, which was i¬rst isolated in 1815 and obtained in crystalline form in 1870. In 1910, the feruloylmethane skeleton of curcumin was coni¬rmed and synthesized by Goel et al. What is more, extensive research over the last half century has revealed several important functions of curcumin. Such effects include antioxidant, anti-ini¬ammatory, antimicrobial, hepatoprotective, anticarcinogenic, thrombosuppressive and cardiovascular.
Highlights
Curcumin, a yellow pigment present in turmeric has been shown to exhibit numerous activities, which was first isolated in 1815 and obtained in crystalline form in 1870
The most key biological activity of curcumin related to neuroprotection is its anti-oxidant function that can protects substantia nigra neurons, increases striatal dopamine level and chelates Fe2+ in the 6-hydroxydopamine rat models of Parkinsons disease (PD) [3]
Several studies in different experimental models of PD strongly support the clinical application of curcumin in PD
Summary
Emerging Role of Curcumin in Parkinson's Disease A yellow pigment present in turmeric has been shown to exhibit numerous activities, which was first isolated in 1815 and obtained in crystalline form in 1870. Extensive research over the last half century has revealed several important functions of curcumin.
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