Abstract
Objective: Embryo biopsy methods, particularly mechanical partial zona dissection (PZD) and acidified Tyrode’s solution (ATS) have been compared by several authors. These two methods are both believed to be similarly efficient and safe in experienced hands. We believe that the “embryo biopsy medium” (EBM) used in this step is just as important as the method employed for zona opening, and its effect on the embryo may be easily overlooked. This retrospective data analysis study compared the pregnancy rate using two kinds of EBM used at our center from 03/01/2002 to 10/31/2003 for aneuploidy screening cases using Fluorescent in Situ Hybridization (FISH).
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