Abstract
The aim of this work is to present a ready to industrialize low-cost and easy-to-install bleeding detector for use in intraoperative electron radiation therapy (IOERT). The detector works in stand-alone mode and is embedded into a translucent polymethylmethacrylate (PMMA) applicator avoiding any contact with the patient, which represent a novelty compared to previous designs. The use of this detector will prevent dose misadministration during irradiation in the event of accumulation of fluids in the applicator. The detector is based on capacitive sensor and wireless power-supply electronics. Both sensor and electronics have been embedded in the applicator, so that any contact with the patient would be avoided. Since access to the tumor can be done through different trajectories, the detector has been calibrated for different tilting angles. The result of the calibration provides us with a fit curve that allows the interpolation of the results at any angle. Comparison of estimated fluid height vs real height gives an error of 1mm for tilting angles less than 10° and 2mm for tilting angles greater than 15°. This accuracy is better than the one required by clinic. The performance of the bleeding detector was evaluated in situ. No interference was observed between the detector and the beam. In addition, a user-friendly mobile application has been developed to help the surgical team making decisions before and during irradiation. The measurement provided by the mobile application was stable during the irradiation process.
Highlights
Intraoperative radiation electron radiotherapy (IOERT) is a tech nique that is currently on the rise [1]. This is due to the development of portable electron linear accelerators that are equipped with adequate self-shielding that allows their use in conventional operating rooms
These curves in turn have been obtained by representing the output voltage Vo as a function of the fluid height, measured on the applicator wall with respect to the horizontal surface
This function is programmed in the mobile application to determine the fluid height in the applicator
Summary
Intraoperative radiation electron radiotherapy (IOERT) is a tech nique that is currently on the rise [1]. This is due to the development of portable electron linear accelerators that are equipped with adequate self-shielding that allows their use in conventional operating rooms. The FLASH effect in radiotherapy is a radiobio logical effect characterized by a loss of radiobiological effectiveness on healthy tissue and an unaltered therapeutic efficacy on tumour tissue. This effect is obtained by delivering the dose with an extremely high dose rate (above 40 Gy/s) [8]
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