Abstract
Background and Aims: Cardiovascular disease, the leading cause of death worldwide, is in the majority of cases a result of atherosclerosis. However, only half of all cases of atherosclerosis incidence can be explained by established risk factors including hypercholesterolemia (HCL). Hyperhomocysteinemia (HHcy) is an independent risk factor for atherosclerosis and strongly correlates with cardiovascular mortality. HHcy is found in 5-10% of the general population and up to 30% of the elderly, and is due to genetic defects or vitamin deficiency related to homocysteine (Hcy) degradation.
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