Abstract

The elemental analysis of very low liquid sample volumes through plasma spectrometry (i.e. inductively coupled plasma atomic spectrometry (ICP-AES) and ICP mass spectrometry (ICP-MS)) is a challenging research subject because, in many fields, the sample volume is the limiting factor for the analysis. The system for introducing liquid samples has been modified in order to perform this kind of analysis and different choices have appeared. Two general solutions are reviewed: (i) the continuous introduction of the solution into the plasma as an aerosol; and, (ii) the discrete introduction of the sample into the system. Included in the first group are several nebulizers, spray chambers and desolvation systems that have been developed to work at low liquid-flow rates (i.e. below 100 μl/min). The second group includes electrothermal vaporization (ETV) of a low sample volume and its further transport to the plasma. We review these systems and discuss the analytical problems associated with each.

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