Abstract

Introduction: Previously, we demonstrated that skeletal myoblast (SM) based engineered tissue constructs (ETC) applying specific culture conditions can augment the intra-cardiac conduction system, i.e. for the treament of AV conduction block. However, the mechanical and contractile properties of SM based ETC remain largely unexplored. Here, we present force measurement analyses of ETC as an essential prerequisite for potential treatment of the failing heart.

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