Abstract
Particle size-number distributions of aerosol from e-cigarettes (0 and 14mgmL-1 nicotine) were compared with conventional cigarettes. Results were used to provide age-specific (9-21years) dosimetry estimates applying the MMPD model. After a 2-s puff, total number doses (D Tot ) were highest for 9years of age (6.01×1010-1.31×1011 particles) and lowest for 18years of age (4.69×1010-1.06×1011 particles). Such doses represented about 19-45 and 25-100% of the relevant daily doses of not smoking individuals, respectively, in tracheobronchial (TB) and alveolar (A) regions. D Tot for the e-cigarettes were about double that for conventional cigarette. Deposition densities and daily volume of e-cigarette liquid deposited per unit surface area were maximum at lobar bronchi, highest for 9years and lowest for 21years age.
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