Abstract
The peripheral blood of four patients with acute myelogenous leukemia was used to study the relationship between the granules and the Auer bodies. Electron microscopic observation revealed the picture of fusion of these organelles. Pictures such as an unusually developed granule with changed internal structure, and the developmental process of the Auer body were observed. It was concluded that the origin of the Auer body was a granule, as previously reported, and they were classified into three types according to their different internal structures. No particular relation between the size of the granule and the degree of electron density was noticed, though some authors Indicated that the size of the granule was related to the electron density. Several microtubules with diameter of 60 A which run parallel to each other were frequently seen In the granules. It was not clarified as to what kind of granule corresponded to the azur granule in this study. ACTA PATH. JAP. 22:509–515, 1972.
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