Abstract
The human antral gastrin cell was identified and characterized by light and electron microscopy, using γ G-immunoglobulins-containing antibodies to human gastrin I labeled with horseradish peroxidase. The gastrin cells identified by this method were shown to be the identical cells as those previously described using fluoresceinated antibodies to human gastrin I. The gastrin cells contained specifically stained round, cytoplasmic granules 150 to 200 m μ in diameter. The other endocrine-like cells of the human antrum were identified and ultrastructural criteria were established for distinction of these cells from the gastrin cells.
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