Abstract

The techniques of electromyography and nerve conduction are clinical tools to study normal and abnormal behavior of the peripheral nervous system. With these techniques, peripheral nerve disease can be classified according to acuity and pathophysiology, and localization of particular nerve lesions can be accomplished. Primary muscle disease can also be identified, and evidence for the presence of ongoing inflammation can be gathered. Although these techniques are now part of the accepted clinical evaluation of patients with peripheral nerve or muscle disease, they also can be used as research tools, to noninvasively study ion channel function, single axon responses, changes in single motor units as a function of a variety of disease states, and central conduction pathways.

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