Abstract
Due to their ability to interact with their environment, the interest in micro- cantilever sensors in biological or chemical applications is increasing. Moreover measurement of the sensor bending induced by molecular adsorption is improved by electrochemical actuation of the cantilever. This is why modelling the electro-elastic coupling is a key issue. Different methods are used to measure the bending induced by this electrochemical actuation. Among them, multiple wavelengths imaging microscopy provides full-field measurements. The local surface electrical charge density and the deformation field are obtained by decoupling wavelength-dependent and -independent contributions to the collected intensity. Based on a modelling of the electro-elastic coupling and on these full-field measurements, an identification method of the coupling parameters of the system is proposed herein.
Highlights
Molecule recognition in biology is widely performed with fluorescent or radioactive tags due to the low detection level they provide [1]
The resonance frequency of the micro-cantilever is monitored and allows for mass variation detection induced by molecular adsorption [4,5]
The out of plane displacement field and a field assumed proportional to the free strain field are obtained by multiple wavelengths imaging microscopy
Summary
Molecule recognition in biology is widely performed with fluorescent or radioactive tags due to the low detection level they provide [1]. Their preparation and the interest molecules modification require costly and time consuming procedures [2]. The resonance frequency of the micro-cantilever is monitored and allows for mass variation detection induced by molecular adsorption [4,5]. The optical lever technique allows to read the out of plane displacement at the cantilever tip. This is used to detect DNA molecules by hybridization [7]. The displacement induced by adsorption is very low and difficult to measure
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
