Ejaculate quality and testosterone levels in men vaccinated with Gam-Covid-Vac (Sputnik-V)

Abstract

Background. COVID-19 disease is often severe, and therefore it is rational to use vaccination. But many men have concerns about its effect on fertility, which requires clarification. Aim. Evaluation of the quality of the ejaculate and the levels of total testosterone during the use of the Gam-Covid-Vac vaccine (Sput-nik-V). Material and methods. The pilot observational prospective study included 30 men with normozoospermia and 30 with pathozoosper-mia, who have been vaccinated with Gam-Covid-Vac. The study period was from March 2021 to June 2021. The total blood testosterone level and parameters of ejaculate quality were determined. The comparisons were carried out in dynamics, the differences were considered statistically significant at p<0.05. Results. The effect of vaccination on total testosterone levels was not revealed. The effect of vaccination on the parameters of the ejaculate quality in patients with pathozoospermia was not revealed. In the group of patients with normozoospermia among patients with impaired sperm motility, which was –5[–7;–3]% and had no clinical significance, an increase in temperature after vaccination was statistically significantly more frequent. Conclusion. There was no negative effect of the vaccine on total testosterone levels and ejaculate quality. © 2021, Media Sphera Publishing Group. All rights reserved.