Abstract
Livestock can sustain expected levels of productivity if the disease is controlled successfully. Rabbit coccidiosis is the major disease-causing high mortality and morbidity. Since no vaccine is available, the eradication is primarily based on careful management combined with medication in feed or water. Chemical coccidiostat is not only raising antibiotic resistance. It also adds environmental contamination since antibiotic is secreted onto land and water. In this report, we attenuate Eimeria piriformis and used it as the vaccine candidate for New Zealand rabbits in Yogyakarta, Indonesia. 90% of rabbits immunized with live attenuated E. piriformis showed no severe signs when challenged with wild type containing 5 x 105 oocyst. The use of live-attenuated E. piriformis is promising as coccidiosis prevention and control program. The strategy would reduce the continuous usage of chemoprophylactic substances in rabbit husbandry and therefore contribute in reducing environmental contamination of antibiotics
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