Abstract
Fifteen N-propargylic β-enaminones were synthesized from the reaction of propargyl amines [4X-PhNHCH2C≡CH, where X = H, Me] and 4-alkoxy-1,1,1-trihalo[ethoxy]-3-alken-2-ones [RC(O)CH=C(R)OMe, where R = CF3, CCl3, CO2Et and R = Me, Et, Pr, Bu, i-Pent, CH2CH2CO2Me]. The methodology described herein proceeded smoothly and furnished the products in good to high yields (70-95%).
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