Abstract
An efficient synthesis of new series of various 3-aryl, 3-heteroaryl, and 3-styryl-4H-pyrido[1,2-a]pyrimidin-4-ones by palladium-catalyzed Suzuki-Miyaura cross-coupling reactions using microwave irradiation is described. The coupling process is tolerant of electron-poor, electron-rich, and bulky boronic acid derivatives, and leads to the desired products in good yields.
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