EFFICIENCY OF NUTRITIVE SUPPORT IN ACUTE CEREBRAL INJURIES IN THE CONDITIONS OF INTENSIVE THERAPY IN THE AGE ASPECT

Abstract

Introduction. Metabolic needs vary at different ages. The development of a critical state is changing the need for energy-plastic support. The most energy-dependent organ is the brain, the formation of which in childhood directly depends on the effectiveness of nutritional support. Aim: to evaluate the effectiveness of nutritional support in acute cerebral injuries in infants under intensive care. Materials and methods. Was conducted an observational analytical cohort study of 30 children aged 0 days to 3 months, with the consequences of hypoxic-ischemic encephalopathy (main group) and 20 relatively healthy infants. The delayed gastric evacuation, abdominal bloating, the level of total protein and blood glucose were determined. The results of the study. Abdominal distention was observed in 46.6% of the main group infants, and delayed evacuation of gastric contents was observed in 40% of children (χ2 = 13; p<0.001 and χ2 = 10.5; p<0.001 relative to the comparison group, respectively). In infants of the main group, the indicator of total protein was 58 (38; 62) g / l and was lower relative to the comparison group (p = 0.005). The same changes occurred in the blood glucose level: 3.05 (1.75; 3.7) mmol / l in the main group (p = 0.02). Biochemical parameters correlated with the presence of clinical signs of disorders of the digestive tract. Conclusion. In acute cerebral injuries, there is a development of signs of gastrointestinal insufficiency. These disorders correlate with impaired protein and carbohydrate metabolism and lead to a decrease in total protein and glucose, which indicates a decrease in the effectiveness of nutritional support for patients, including infants.