Abstract

Objective: To evaluate the efficacy of He-Ne laser in combination with topical clindamycin in the treatment of AV at 108 Military Central Hospital from Oct 2015 to Aug 2016. Subjects and Methods: 61 patients with AV were divided into 2 groups: Group 1: 31 patients were treated with He-Ne laser in combination with topical Clindamycin, Group 2: 30 patients were only treated with topical clindamycin. Laser HE-NE was applied 2 times/week for 6 weeks. Result: After 3 months of treatment Group 1: very good—51.6%, good—48.4%. Group 2: very good—30%, good—50% and moderate—20%. Conclusion: The combination of He-Ne laser with topical clindamycin shows more rapid clinical improvement compared to topical clindamycin alone in the treatment of mild and moderate AV.

Highlights

  • Acne vulgaris is a very common skin disease in both men and women with about 80% of adults

  • Subjects and Methods: 61 patients with AV were divided into 2 groups: Group 1: 31 patients were treated with Helium-Neon laser (He-Ne) laser in combination with topical Clindamycin, Group 2: 30 patients were only treated with topical clindamycin

  • Results after 2 months of treatment in Table 2 show that the proportion of patients in the HENE + Clindamycin group was very good at 29.0%, good 64.5%, moderate 6.5%, while patients in the Clindamycin group only achieved good or moderate level p < 0.05

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Summary

Introduction

Acne vulgaris is a very common skin disease in both men and women with about 80% of adults It most often affects adolescents from 13 to 25 years old [1] [2]. The pathogenic factors of AV hyperkeratosis might include infra-infundibulum, sebaceous duct, hyperactivity of sebaceous gland, hyperseborrhea, hyperproliferation of P. acnes, inflammation and immunological host reaction. Factors such as family factors, psychological impact, environment, diet, personal hygiene greatly affect the incidence of acne [3]. This study was conducted with the objective to evaluate the efficacy of He-Ne laser combined with topical clindamycin in the treatment of acne vulgaris.

Demographics and Clinical Symptoms before Treatments
Compared Results from Weekly Treatments
Discussion
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