Abstract
Objective To explore the efficacy of adaptive support ventilation on the respiratory mechanics of patients with chronic obstructive pulmonary disease(COPD)with hypercapnic(TypeⅡ) respiratory failure.Methods Twenty-six patients with COPD with TypeⅡrespiratory failure had vetilated by the same ventilator.They were all applied pressure control synchronized intermittent mandatory ventilation plus inspiration pressure support(P-SIMV+PSV)and adaptive support ventilation(ASV)respectively during the stage.The parameters of respiratory mechanics,hemodynamics and blood analysis were compared during P-SIMV+PSV and ASV.Results Total respiratory rates decreased significantly (P 0.05).Conclusions In patiens with COPD with Type Ⅱ respiratory failure,ASV may automatically adjust inspiratory pressure,the tidal volume increases and respiratory rate decreases with the respiratory mechanics of each patient,which may not affect hemodynamics and vital signs. Key words: Adaptive support ventilation; Hypereapnic(Type II)respiratory failure; Chronic obstructive pulmonary disease; Respiratory mechanics
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