Abstract

IntroductionThere has been growing evidence to support the hypothesis that inflammation is involved in the pathogenesis of schizophrenia.ObjectivesThe aim of the present literature review was to assess the efficacy of acetylsalicylic acid (ASA) as an adjuvant agent in the treatment of an acute exacerbation of schizophrenia.MethodsWe searched randomized clinical trials based on regular searches of MEDLINE, Embase, PubMed.ResultsWe included four studies. The results were in favor of the efficacy of ASA in the study where authors targeted early psychosis. Illness duration seems to predict response to anti-inflammatory agents.ConclusionsFurther studies of early stages of schizophrenia are helpful.Disclosure of InterestNone Declared

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