Abstract
This study is a randomized, placebo-controlled, double-blinded trial performed to investigate the effects of a dietary supplement containing a mixture of Boswellia serrata Roxb., chlorophyll, green tea extract, glucosamine, chondroitin sulfate, hyaluronic acid, and further in the manuscript: non-hydrolised type II collagen in dogs with osteoarthritis (OA). A total of 40 dogs were enrolled in the study, they were randomly divided in control (CTR) and treatment (TRT) groups. The TRT group received the dietary supplement for 60 days. The CTR group received a placebo for the same number of days. All the subjects had veterinary evaluations during the trial and owners were requested to fill in questionnaires on chronic pain using the Helsinki Chronic Pain Index. The product was easy to administer and no side effects were reported. Combining results from veterinarian and owner evaluations, the tested product proved to be significantly beneficial in alleviating pain and in reducing the clinical signs in dogs with OA.
Highlights
Osteoarthritis (OA) is a common condition in humans and pets
Animal examination performed by veterinary specialists using radiographs, clinical signs, type and degree of lameness, and OA risk factors can help predicting the risk of joint degradation [3]
We investigated the effect on chronic pain and clinical signs of a supplement (Confis Ultra, Candioli s.r.l., Italy) containing a mixture of Boswellia serrata Roxb., chlorophyll and green tea extract in addition to some chondroprotectants (Chondroitin sulfate, glucosamine and hyaluronic acid) on dogs affected by OA
Summary
Osteoarthritis (OA) is a common condition in humans and pets. It is characterized by a change in tissues of synovial joints, with chronic pain and disability as a result of the articular cartilage deterioration. Trauma, genetic predisposition, and excessive exercise could be common causes of OA; while the breed, gender, animal size and overweight are known risk factors [1, 2]. Common findings in dogs diagnosed with OA are: hypertrophy of bone at the margins, degeneration of the cartilage, and changes in the synovial membranes. Animal examination performed by veterinary specialists using radiographs, clinical signs, type and degree of lameness, and OA risk factors can help predicting the risk of joint degradation [3]. Several questionnaires have been developed and validated to obtain valid and comparable information
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