Abstract
PET/CT offers the most advanced possibilities for visualization of non-small cell lung cancer (NSCLC) nowadays. 18F-FDG PET/CT plays a significant role in staging of NSCLC, choosing of treatment strategy, planning of radiation therapy and evaluation of its efficacy. Clinical observation of the patient with non-small cell lung cancer with response assessments by 18F-FDG and 18FFLT PET/CT during the course of chemoirradiation is demonstrated. There was a correlation between 18F-FDG and 18F-FLT PET/CT with advantage of 18F-FLT PET/CT for early response evaluation. The combination of 18F-FDG and 18FFLT PET/CT will be helpful to personalize chemoirradiation and to predict response more accurately. The presented clinical case demonstrated the possibilities of 18F-FDG and 18F-FLT PET/CT for assessment of treatment efficacy in patient with non-small cell lung cancer.
Highlights
Метод позитронной эмиссионной томографии, совмещенной с компьютерной томографией (ПЭТ/КТ), на сегодняшний день предоставляет самые большие возможности для визуализации при немелкоклеточном раке легкого (НМРЛ)
PET/CT offers the most advanced possibilities for visualization of non-small cell lung cancer (NSCLC) nowadays. 18F-FDG PET/CT plays a significant role in staging of NSCLC, choosing of treatment strategy, planning of radiation therapy and evaluation of its efficacy
There was a correlation between 18F-FDG and 18F-FLT PET/CT with advantage of 18F-FLT PET/CT for early response evaluation
Summary
Совмещенной с компьютерной томографией (ПЭТ/КТ), на сегодняшний день предоставляет самые большие возможности для визуализации при немелкоклеточном раке легкого (НМРЛ). Представлено клиническое наблюдение больного местнораспространенным НМРЛ с оценкой эффективности на разных этапах химиолучевой терапии на основании данных ПЭТ/КТ с 18F-ФДГ и 18F-фтортимидином. По результатам наблюдения можно отметить, что данные ПЭТ/КТ с 18F-ФДГ и 18F-фтортимидином в целом коррелируют между собой, при этом возможность проведения исследования с 18F-фтортимидином сразу после завершения лучевой терапии обеспечивает преимущество данного метода в ранней оценке эффективности лечения. Данное наблюдение демонстрирует возможности ПЭТ/ КТ с 18F-ФДГ и 18F-фтортимидином в оценке эффективности лечения НМРЛ на клиническом примере.
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