Abstract
Age-related decline in erectile function is a noted phenomenon worldwide. A variety of medicinal plants have been identified as having strong aphrodisiac p roperties along with the ability to improve erectil e functioning. Kaempferia Parviflora (KP) has famous as a Thai Viagra and use it to incr ease male impotency. However, there is limited scientific evi dence regarding the efficacy of this herb on this i ssue in aging healthy men. This study therefore investigate d the effect of KP extract administration on erecti le response of male elderly volunteers. Total 45 male healthy elderly volunteers will be divided into 3 s eparated groups including placebo and the different doses of ethanolic extracts of KP (25 and 90 mg) once daily at a period of 2 months. The erectile function tests inc luding the response latency time to visual erotic s timuli, size and length of penis both in flaccid and erection st ates were assessed after single administration, 1 a nd 2 months of treatment. In order to investigate the possible underlying mechanism, we also determined the alteration of testosterone, FSH and LH concentrations. KP at a do se of 90 mg day -1 treated group exhibited a significant enhanced all parameters after 1 and 2 months of tre atment. Moreover, the penile length at erection st ates and the response latency to sexual erotic stimuli appea red to be the parameters that showed significant ch anges during the delay period. Unfortunately, our study f ailed to show the significant changes on hormones concentration. Our study clearly demonstrates that KP is a potenti al resource for the development of nutraceutical compound against aged related male er ectile dysfunction.
Highlights
The effects of Kaempferia Parviflora (KP) extract on penile circumference and length both in flaccid and erection states were shown in Fig. 1-4 respectively
After 1 and 2 months of treatment with KP at a dose of 90 mg day−1 experienced a statistically significant increase in the length and width of their penis both in flaccid and erection states when compared with the placebo treated group (p
Male impotence was studied in aging healthy men to further understand the role of KP extract as an aphrodisiac
Summary
Several type of treatment is claimed in the modern medicine but due to serious side effects and Sexual relationships are some of the most important higher cost, search of natural supplement from social and biological relationship in human life. Male medicinal plants as an aphrodisiac substance is impotence called Erectile Dysfunction (ED) is a significantly increased (Yakubu et al, 2007). Thai folk use the inability to develop or maintain penile erection rhizome of this plant as a traditional medicine to increase sufficiently while engaging in sexual intercourse male libido, alleviate male impotency, induce an Corresponding Authors: Wathita Phachonpai, Division of Physiology, School of Medical Science, University of Phayao, Phayao, 56000, Thailand Tel: 66-54-466666 Fax: 66-54-466690. We provided evidence that oral administration of KP extract, a Thai medicinal plant reputed for aphrodisiac activity and enhanced the expression of male sexual behaviors in aging rats (Wattanathorn et al, 2012). The present study is carried out to determine the effect of KP extract on the erectile function in the male elderly volunteers
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
