Abstract
Background: Low dose dopamine is widely used during the perioperative pend to preserve renal perfusion. Low dose dopamine (3-5g/kg/min) was administrated to partial hepatectomy patients and BUN, creatinine in serum were measured to determine the effects of low dose dopamine on renal function. Methods: Liver group (n = 28) were administered low dose dopamine (3-5g/kg/min) and the stomach group (n = 23) were not administered any vasoactive drugs during the operation. Perioperative plasma BUN, and creatinine, creatinine clearance, BUN/creatinine ratio, serum Na and K, and central venous pressure (CVP) were checked 3 times, justafter starting operation, 4 hours after starting the operation, and at PACU for both grops. We also evaluated intravascular volume status using the CVP and the BUN/creatinine ratio. Changes in BUN, and creatininc dvcl during the operation in both group were compared. All the patients in this study were confirmed as having euvolemia by C'P and BUN/creatinine ratio. Results: Urine volume increased significantly in the liver group withlow dose dopamine compared to the stomach group (P level decreased significantly (P
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