Effects of two different administration methods of heparin on the survival rate of severed finger replantation

Abstract

Objective To evaluate the effects of two different administration methods of heparin on the survival rate of severed finger replantation. Methods From March 2010 to January 2015, the operation of single severed finger replantation was performed on 104 patients in emergency department of our hospital. According to the different administration methods of heparin after operation, they were divided into intravenous injection group (group A) and intravenous drip group (group B), with 52 cases in each group. The incidence of vascular crisis, the survival rate of replantation and the adverse reactions were observed postoperatively. The patients were follow-up for 2 months. Results There was no significant difference between two groups in the incidence of vascular crisis and the survival rate of replantation, and the adverse reactions in intravenous injection group were significantly lower than those in intravenous drip group. Conclusion There was no significant difference in the incidence of vascular crisis and the success rate of replantation after operation between intravenous injection of heparin and intravenous drip of heparin. However, intravenous injection can reduce the adverse reactions. Key words: Replantation; Heparin; Administration method; Vascular crisis; Adverse reaction