Abstract
Dermal papillae isolated from anagen hair bulbs of three healthy male subjects with normal hair pattern and fibroblasts derived from the mesenchymal root sheath of the same hair follicles were separately grown in culture. Both hair bulb papilla cells (PC) and root sheath fibroblasts (RSF) were subcultured in a medium containing two different doses of testosterone (30 and 300 ng/ml), dihydrotestosterone (30 or 300 ng/ml) or estradiol (1 and 10 ng/ml). The number of PC and RSF was counted every second day over two weeks. Growth rates of the PC and RSF were inhibited by doses of both testosterone and dihydrotestosterone. Especially the growth rates of PC were markedly lower than those of RSF at the higher doses. Estradiol was ineffective in both cell lines.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
