Abstract

Objective To explore the effects of subclinical hypothyroidism (SCH) during pregnancy on maternal-infant outcomes. Methods Clinical data of 90 SCH puerperae and 90 puerperae with normal thyroid function who had production inspection and delivered in Department of Obstetrics and Gynecology of Zhengzhou Third People’s Hospital from November 2016 to November 2018 were retrospectively analyzed. SCH puerperae were included in SCH group, and puerperae with normal thyroid function were assigned to control group. Pregnancy outcomes and complications of puerperae and neonatal adverse outcomes were analyzed in the two groups. Results The full-term yield of maternal pregnancy outcomes in SCH group was lower than that in control group, and the preterm birth rate and abortion rate were higher than those in control group (P 0.05). After delivery, the incidences of neonatal adverse outcomes (fetal growth restriction, fetal distress) in SCH group were higher than those in control group (P 0.05). Conclusions SCH can increase the risk of maternal-infant adverse outcomes. Thyroid function screening in early pregnancy is necessary in the treatment of pregnant women with SCH, and it reduce the maternal-infant adverse outcomes. Key words: Pregnancy; Subclinical hypothyroidism; Maternal-infant outcomes

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