Abstract

Fabrication of polymer microfluidics devices such as micromixer by injection molding becomes popular increasingly. It is always involved with the replication of micro-channels for fluids. The quality control of the produced micro-channels is a key issue in the microfluidics devices fabrication. This paper studies the effects of processing conditions on the cross-sectional profile and the dimensions of the micro-channel such as its width and depth. Design of experiment (DOE) using Taguchi method and a L18 (21 × 37) orthogonal array is used to carry out the optimization of the processing conditions in order to achieve the closest micro-channel width to the micro-feature width of the mold insert. Eight processing parameters are considered in DOE and their significances are investigated in analysis of variances (ANOVA). They are pre-drying, melt temperature, mold temperature, injection velocity, injection pressure, holding pressure and holding time, as well as cooling time.

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