Abstract
Objective To compare the effects of the multi-time patch biopsy under the conventional white light imaging endoscopy (C-WLI) and precise targeted biopsy under magnifying narrow-band imaging endoscopy (M-NBI) on the ESD operation of early gastric cancer and intraepithelial neoplasia. Methods Patients were divided into C-WLI group and M-NBI group, 36 cases in each group. The ESD operations of 2 groups were compared quantitively. Results The mean frequency of selecting biopsy specimen in M-NBI group was (1.45±0.62), significantly lower than that of C-WLI(9.62±2.25) (P 0.05). Whereas submucosal injection time, mucosal dissection time, hemostasis time, wound processing time of M-NBI group were significantly shorter than those of C-WLI group (P<0.01). Conclusion Precise targeted biopsy under M-NBI can obviously shorten the time of the endoscopic submucosal dissection (ESD) operation, with small quantity of biopsy tissues and high positive rate of tissues. Key words: Biopsy; Precancerous lesion; Early gastric cancer; Endoscopic submucosal dissection
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