Abstract
We have previously found that <i>in vitro </i>addition of autoclaved measles virus (AMV) suppressed lymphocyte proliferation. The characteristics of this response were further explored. Proliferation induced by both PHA and PWM was depressed as was <sup>14</sup>C-amino acid incorporation. AMV present in the medium for only the first 2–4 h of culture lead to prominent suppression. Suppressive activity was found in both dialyzable and non-dialyzable fractions of AMV. No evidence of cytotoxicity was seen by three different measurements.
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