Abstract

SummaryMescaline, injected intravenously and intraperitoneally into dogs and cats and into the lateral ventricle of the brain of cats, produced acute autonomic effects followed by catatonia. These responses appeared to be altered or prevented by pretreatment with the ataraxic agents chlorpromazine, reserpine, and azacyclonol.We are indebted to Dr. Robert L. Craig and Mr. Robert G. Bianchi for implanting the cranial cannulae and to Dr. Kurt Rorig for synthesizing the azacyclonol.

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