Abstract

Objective To investigate the effects of low-frequency repetitive transcranial magnetic stimulation on motor function and executive function in patients with Parkinson’s disease. Methods Ninety-four patients with Parkinson’s disease admitted to the Third People’s Hospital of Heze from April 2016 to March 2018 were selected and divided into two groups by single blind method, with 47 patients in each group. The control group was treated with levodopa and benserazide hydrazine tablets and selegeran tablets. The observation group was treated with low-frequency repetitive transcranial magnetic stimulation based on the treatment for control group. After 2 months of treatment, motor function, autonomic nervous function and executive function were compared between the two groups. Results After treatment, motor function (UPDRS Ⅲ), autonomic nervous function (SCOPA - AUT) score of the two groups was lower, and the observation group had lower scores than the control group (P<0.05). After treatment, rapid verbal retrieve, clock drawing test and trail marking test scores of the two groups were higher than those before treatment, and the differences between the two groups were statistically significant (P<0.05). Conclusions On the basis of conventional drug therapy, low-frequency repetitive transcranial magnetic stimulation can not only improve autonomic nervous function and motor function, but also enhance executive function in patients with Parkinson’s disease. Key words: Parkinson's disease; Low-frequency repetitive transcranial magnetic stimulation; Motor function; Executive function

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