Abstract
Lyotropic phases of hydrated 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) are generally considered as models of biological membranes. Effects of lauric acid (LA) and fenspiride (FS) on DPPC membrane were studied by differential scanning calorimetry and fluorescence spectroscopy with environment-sensitive probe PH7 (2-(2'-hydroxy-phenyl)-phenanthro[9,10-d]-1,3-oxazole). FS decreases pretransition- and gel-to-liquid crystal phase transitions temperatures of DPPC membrane and extends temperature range of ripple phase, contrary to LA. Meanwhile, LA and FS cause membrane fluidization in the gel and liquid crystalline phases, with perturbation effects more pronounced for LA.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.