Abstract
Objective To evaluate effects and safety of L-carnitine supplementation on maintenance hemodialysis patients(MHD)with camitine deficiencies.Methods sixty MHD patients were recruited,they had undergone hemodialysis for at least two years before the study and were in a stable clinic status,they were randomly divided into two groups.For the therapy group.L-camitine 1.0 g intravenously infuse was given after every dialysissession.The observed course was 3 months.For the control group.intravenous injection normal saline was given.Results For the therapy group,improve clinical symptom s significantly,the maintenance does of rHuEPO was decreased.Hb,Hct,serum albumin,transferrin were all raise.carnitine deftciencies effects were negligible.Conclusion L-caruitine Can L-carnitine to MHD patients with caruitine deficiencies can increase plasma free carnitine level. Key words: Maintenance hemodialysis; L-carnitine; Quanty of life
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