Abstract

1. Specific inhibition of intestinal alkaline phosphatase by L-phenylalanine was shown in eels adapted to both seawater and freshwater. 2. L-phenylalanine-sensitive alkaline phosphatase was demonstrated histochemically at the luminal surface of the sea water eel intestine. 3. Net absorption of water, Na + and Cl − by the everted intestine was reduced significantly by adding L-phenylalanine to both internal and external Ringer incubation medium. 4. No appreciable change in transepithelial potential difference was observed by adding 30 mM L-phenylalanine to NaCl, sulfate or choline Ringer solutions.

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