Abstract

This study was aimed to investigate the effect of green tea extract (GTE) combined with brisk walking on lipid profiles and the liver function in overweight and obese men. Twenty-four participants were randomized to either the GTE group or the placebo group for 12 weeks with a 4-week follow-up. The walking program consisted of four 60-min-sessions/week and all participants were asked to consume two GTE (150mg) or placebo tablets daily. After 12-week intervention, GTE group resulted in a significant difference in the low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) levels when compared to placebo group (P < 0.01). There was also a significant reduction in the aspartate aminotransferase levels (P < 0.01) in the GTE group, but no change in the placebo group (P >0.05). There was no change in the triglyceride or high-density lipoprotein cholesterol (HDL-C) levels in the placebo group, but a significant reduction was noted in the HDL-C levels in the GTE group (P < 0.05). GTE combined with brisk walking resulted in a significant change in the LDL-C and TC levels, however, a significant reduce in HDL-C in the GTE group. The study has a more positive effect on the liver function than brisk walking alone.

Highlights

  • The prevalence of overweight and obesity has increased dramatically over the last four decades (Jaacks et al 2019)

  • The between-group analysis of co-variance (ANCOVA) As shown in Table 2, there was a significant difference in the low-density lipoprotein cholesterol (LDL-C) levels between the green tea extract (GTE) group and placebo group (P < 0.05)

  • There were no significant differences in the high-density lipoprotein cholesterol (HDL-C) and TG levels and the liver function (ALT, AST and TBIL levels) between the GTE group and placebo group

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Summary

Introduction

The prevalence of overweight and obesity has increased dramatically over the last four decades (Jaacks et al 2019). Studies (Piepoli et al 2016, Oliveros et al 2014) have reported that obesity is associated with LDL-C, HDL-C, TG, and TC as important risk factors for the development of dyslipidemia, hyperlipidemia, and atherosclerosis. As physical activity and GTE have been shown to be associated with the management of obesity and lipids cholesterol, there is great interest in exercise and GTE modifications to help improve the body composition and treat chronic diseases. Increased physical activity is an important component of therapy for obesity management. Brisk walking as a simple, economic, and safe form of exercise is the most popular moderateintensity aerobic physical activity for both men and women, especially for most middleaged and/or overweight and obese individuals (Siegel et al 1995).

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