Effects of Gamma Radiation Exposure to Reduce of Monocyte Count and Serum Level of IFN-γ in Industrial Radiography Workers

Abstract

Gamma radiation exposure is induce immunosuppresive against the immune system. The aim of this study was to analyze the effects of gamma radiation exposure to reduction monocyte count and serum level of IFN-γ in industrial radiography workers. The method of the study was an observational research with longitudinal study design. Eleven industrial radiography workers were included in this study. Gamma radiation exposure was measured by using Pocket Gamma Dosimeter. Laboratory tested for monocyte count were using Differential Cell Count method and serum level of IFN-γ was using ELISA method. The result showed that gamma radiation exposure was not exceed dose limited value (NBD) PerkaBAPETEN No. 4 Year 2013 the mean dose was 0,0088500 mSv. There was no difference among lymphocyte monocyte count (t-value = 0,811) and serum level of IFN-γ (t-value = 0,286) in industrial radiography workers before and after working NDT activities. Characteristics of respondents significantly influence to decreased these dependent variables were history of the disease (infection), nutritional status, and duration of exposure. It is concluded that gamma radiation exposure decrease of monocyte count but not significantly influence to decrease of serum level of IFN-γ. It is suggested to increase partisipation for refresh training, more improving health’s workers through consuming of nutritious food (more low purine and fat) and water, doing sport regularly, and also doing enough rest.