Effects of Dietary Vitamin C on the Growth Performance, Antioxidant Activity and Disease Resistance of Fish: A Review

Abstract

Vitamin C is an essential micronutrient that cannot be synthesized by fish and must be present in fish diets for proper functioning of the physiological conditions. It is required for the biosynthesis of the collagen which is a pre-requisite for the formation of connective tissue and increases the absorption of iron in fish. It prevents various diseases; it is soluble in water and is easily oxidated by heat, light and metal. Most animals can generate vitamin C in sufficient quantities for normal growth and function, but many fish cannot because they lack the enzyme L-gulonolactone oxidase for its manufacture. Vitamin C facilitates the absorption of iron and is necessary for a maximum rate of immune responses and enables a good response to stressors. This updated review presents a general outline of the possible physiological function of vitamin C for fish, with an emphasis on the information on growth performance, antioxidant activity, immune response and disease prevention of fish as well as the synergistic effects of vitamin C with other micronutrients. The diets supplemented with vitamin C promote the growth performance, improve the structure of the intestinal mucosal epithelium, and have a positive impact on the hematological parameter. The addition of different dietary vitamin C to the basal diets significantly improved the growth performance, antioxidant activity, immune response and disease resistance of fish. vitamin C in the aquaculture, having a solid understanding of the positive functions and mechanisms that vitamin C possesses is of the utmost significance.