Abstract
This study was initiated to assess the effect of daily amount of alcohol intake on serum and salivary alpha-amylase activity of regular adult consumers of tchoukoutou and sodabi, two local alcoholic drinks made in Benin. It was a descriptive, cross-sectional and analytical study carried out from 1st of April to 31st of August, 2012. The study population consisted of 50 subjects as regular consumers of tchoukoutou (titrated with 3% of alcohol), 50 regular consumers of sodabi (titrated with 40% of alcohol) and 50 non-consumers of alcohol. Alpha-amylase activity in saliva and serum were measured in each subject. There was no significant difference in the activity of serum and salivary alpha-amylase between consumers of low quantity of tchoukoutou and sodabi (˂ 30 g/ day) on one hand (P = 0.24 and 0.99 respectively), and between moderate consumers (30-79 g/ day) on the other (P = 0.31 and 0.48 respectively). Daily amount of alcohol intake had a positive effect on the serum alpha-amylase activity when taking into consideration the entire group at the threshold of 1%, in tchoukoutou consumers (r = +0.887), and in women sodabi consumers at the threshold of 5% (r = +0.928). Therefore, serum alpha-amylase activity is positively associated with the consumption of these two local alcoholic drinks made in Benin.
Highlights
Alcohol consumption is one of the leading risk factors for death and disability; it accounts for almost 3 million annual deaths globally and 3.9% of years of life lost to disease (GBD 2013 Risk Factors Collaborators, 2015)
This study was initiated to assess the effect of daily amount of alcohol intake on serum and salivary alpha-amylase activity of regular adult consumers of tchoukoutou and sodabi, two local alcoholic drinks made in Benin
There was no significant difference in serum and salivary alpha-amylase activity between consumers of low volumes (˂ 30 g/ day) of tchoukoutou and sodabi on one hand, and between moderate consumers (30-79 g/ day) of tchoukoutou and sodabi on the other (Table 2)
Summary
Alcohol consumption is one of the leading risk factors for death and disability; it accounts for almost 3 million annual deaths globally and 3.9% of years of life lost to disease (GBD 2013 Risk Factors Collaborators, 2015). The adverse effects of alcohol use are well characterized such as liver cirrhosis, injuries and several types of cancer (WHO, 2014; GBD 2013 Risk Factors Collaborators, 2015). Amylase concentrations are highest in the pancreas and salivary glands, amylase is abundant in other organs as well. Salivary and pancreatic forms of alpha-amylase have gained interest in a variety of areas (Zakowski et Bruns, 1985). The use of saliva as of substance abuse/dependence and monitoring of substance levels, including alcohol and tobacco, has gained high attention in the recent years (Soo-Quee Koh and Choon-Huat Koh, 2007)
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