Abstract

Objective To explore the effects of cognitive behavior therapy on anxiety, depression and life quality in inflammatory bowel disease (IBD) . Methods The Cochrane Library, Pubmed, EMbase, CNKI, China biological medicine (CBM) , WanFang were searched and the randomised controlled trials (RCTs) related to cognitive-behavioral intervention for IBD data was collected. The RevMan 5.3 was used in statistical analysis. Results A total of 12 RCTs were enrolled in the study. Results showed that cognitive behavior therapy could improve patients' life quality [WMD=7.78, 95%CI (3.30, 12.27) , P=0.000 7], relieve anxiety [SMD=-0.47, 95%CI (-0.78, -0.16) , P=0.01]and depression [SMD=-2.48, 95%CI (-3.13, -1.83) , P 0.05) . Conclusions In this systematic review, cognitive-behavioral intervention can improve life quality of patients with IBD and can relieve anxiety and depression of patients with IBD in the short term but with no effects in the long term. Key words: Anxiety; Depression; Quality of life; Cognitive-behavioral intervention; Inflammatory bowel disease; Systematic review

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