Abstract

The effects of Bitter cola (Garcinia cola) on haemostatic and biochemical indices of induced male diabetic albino wistar rats were investigated 21 male albino rats (200-230g) were placed into three groups namely Group A (control) Group B ( induced diabetic rats on bitter cola extract) and Group C (induced diabetic rats on dianil reference tablets). At the end of the 28 days feeding on the extracts, blood samples were withdrawn from the animals for investigation. The results from the haemoglobin concentration and packed cell volume indicates a reduction in control rats compared with test rats; Hb Group A 13.8g/dl, group B 10.8g/dl, group C 13.5g/dl, PCV group A 41%, group B 31% group C 41%. The white blood cell count and platelet count were not significantly reduced. WBC for group A 4,800mm 3 , group B 3280 ± 86mm 3 and group C 5,120 ± 666mm 3 . Platelet count group A 216 ± 40×10 9 /l, group B 160±70x10 9 /l, and group C 210± 57x10 9 /l.

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