Abstract
AIM: This study investigated the effects of aqueous leaf infusion of Pterocarpus santalinoides DC on serum lipid profile (SLP) of guinea pigs (GPs). METHODS: Fresh leaves of Pterocarpus. santalinoides were collected in February 2015. Aqueous leaf infusion was freshly prepared daily by soaking dried ground P. santalinoides leaf in hot water for 10 minutes. Twenty female GPs were randomly assigned into 4 groups (A D) of 5 GPs each as follows: Group A distilled water placebo per os (control), groups B, C and D 1.5, 3.0 and 4.5 g/kg body weight (bw) of ground P. santalinoides leaf in 600ml of hot and cooled water per os respectively. Treatment was carried out for 28 days. Assay of SLP was done on days 0 (before treatment), and on days 14 and 28 of treatment following standard procedures. RESULTS: The mean serum high density lipoprotein cholesterol (HDLC) of groups B, C and D rose to almost double its baseline values and was significantly (p < 0.05) higher than that of group A on day 28, while the mean serum low density lipoprotein cholesterol (LDLC) of group D was significantly lower (p
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
