Effectiveness of Antioxidant Compounds in Minaserua Herbal Drink from Bima as a Functional Food on Blood Pressure and Cholesterol Levels

Dyslipidemia, hypertension, and diabetes mellitus have been appropriately highlighted as established predictors of cardiovascular disease. These risk factors have become preeminent targets for influencing cardiovascular risk; their assessment, treatment, and monitoring are major emphases of clinical care, research investigation, treatment guidelines, organization position papers, and measures of physician and hospital performance. Notably, lifestyle risk factors, including dietary habits, physical inactivity, smoking, and adiposity, strongly influence the established cardiovascular risk factors and also affect novel pathways of risk such as inflammation/oxidative stress, endothelial function, thrombosis/coagulation, and arrhythmia. Furthermore, modest alterations of these lifestyle risk factors are achievable and have substantial effects on cardiovascular risk. Thus, basic lifestyle habits should be considered fundamental risk factors for cardiovascular disease. Although efforts to combat established and novel risk factors with pharmacological treatments are important and should continue, we call for a systematic rebalancing of current research, clinical care, and policy efforts to focus more on lifestyle. The rising costs of healthcare and the epidemics of overweight and obesity highlight the inadequacies of our current strategy. Substantially more resources should be directed toward research on lifestyle risk factors, their determinants, and effective interventions to change them. The clinical evaluation and treatment of dietary, physical activity, and smoking habits must become as routine and familiar as assessment of blood pressure, cholesterol, and glucose levels. Major policy initiatives and reimbursement guidelines must also be rebalanced to emphasize lifestyle risk factors. Cardiovascular diseases are leading causes of death and disability among men and women in nearly all nations.1 Identification of persons at higher or lower risk for cardiovascular events is important to facilitate effective use of resources and interventions to reduce disease burden among individuals and in society. Each of the established risk factors for cardiovascular disease—age, gender, dyslipidemia, hypertension, diabetes mellitus, and smoking—have been appropriately highlighted …

Background: Much alternative therapy such as cupping therapy in the community as one of the cheap treatment efforts without side effects makes the challenge and the goal for nursing staff improve nursing services. The unfinished scientific verification of cupping therapy's alternative therapy makes nurses need to prove decreased blood pressure and cholesterol levels in the elderly. Objective: Scientific proof of cholesterol and blood pressure decrease after Cupping Therapy in an elderly group in Wedomartani Village, Sleman Yogyakarta Indonesia. Method: quantitative type with pseudo experimental research design. Pre-test and Post-test nonequivalent control group. The treatment group was given wet cupping therapy, while the control group was given dry cupping. Respondents were selected using a purposive sampling technique. Blood pressure measurement uses a digital tensimeter and cholesterol measurement using a digital blood cholesterol level measuring device. Results: The elderly blood cholesterol levels after the average therapy decreased 42.89 mg/dl, whereas blood cholesterol levels in the control group decreased an average of 20.95 mg/dl. The blood pressure of the elderly systole in the intervention group after the average therapy decreased 10.74 mmHg, whereas the control group's systole blood pressure decreased an average of 1.58 mmHg. Diastole blood pressure in the treatment group decreased 3,48 mmHg, in the diastole blood pressure control group increased 5,26 mmHg. Conclusions: Wet and dry cupping are both significantly associated with decreased blood cholesterol and blood pressure levels, but wet cupping lowers blood cholesterol levels by a mean difference of 21.95 mg/dl and mean systole blood pressure of 3.74 mmHg and pressure diastole blood difference of mean 9.1 mmHg. Keyword: Blood Pressure. Cupping Therapy, Cholesterol, Elderly

Background: Much alternative therapy such as cupping therapy in the community as one of the cheap treatment efforts without side effects makes the challenge and the goal for nursing staff improve nursing services. The unfinished scientific verification of cupping therapy's alternative therapy makes nurses need to prove decreased blood pressure and cholesterol levels in the elderly. Objective: Scientific proof of cholesterol and blood pressure decrease after Cupping Therapy in an elderly group in Wedomartani Village, Sleman Yogyakarta Indonesia. Method: quantitative type with pseudo experimental research design. Pre-test and Post-test nonequivalent control group. The treatment group was given wet cupping therapy, while the control group was given dry cupping. Respondents were selected using a purposive sampling technique. Blood pressure measurement uses a digital tensimeter and cholesterol measurement using a digital blood cholesterol level measuring device. Results: The elderly blood cholesterol levels after the average therapy decreased 42.89 mg/dl, whereas blood cholesterol levels in the control group decreased an average of 20.95 mg/dl. The blood pressure of the elderly systole in the intervention group after the average therapy decreased 10.74 mmHg, whereas the control group's systole blood pressure decreased an average of 1.58 mmHg. Diastole blood pressure in the treatment group decreased 3,48 mmHg, in the diastole blood pressure control group increased 5,26 mmHg. Conclusions: Wet and dry cupping are both significantly associated with decreased blood cholesterol and blood pressure levels, but wet cupping lowers blood cholesterol levels by a mean difference of 21.95 mg/dl and mean systole blood pressure of 3.74 mmHg and pressure diastole blood difference of mean 9.1 mmHg. Keyword: Blood Pressure. Cupping Therapy, Cholesterol, Elderly

Background: Women of reproductive age often experience problems with blood pressure and cholesterol levels. Therefore, researchers innovated in an effort to stabilize blood pressure and cholesterol levels in women of reproductive age by providing an intervention of soy milk. The purpose of this study was to determine the effect of soy milk administration on reducing blood pressure and cholesterol levels in women of reproductive age. Subjects and Methods: This study used a Quasi-Experimental design with Pretest-Posttest Control. The research location was the Pangaribuan Community Health Center, Pangaribuan District, North Tapanuli Regency. Data collection was conducted in June 2025. The two groups consisted of an intervention group receiving 40 grams of soy milk and a control group receiving education on blood pressure and cholesterol levels. The dependent variables studied were blood pressure and cholesterol levels, and the independent variable was soy milk. The analysis techniques used were Repeated Measures ANOVA and Paired Sample T-Test. Results: The average systolic blood pressure in the intervention group after being given soy milk was lower (Mean= 133.92; SD= 10.20) compared to before the intervention (Mean= 143.82; SD= 5.48) and was statistically significant (p <0.001), the average diastolic blood pressure in the intervention group after being given soy milk was lower (Mean= 86.88; SD= 5.08) compared to before the intervention (Mean= 92.88; SD= 5.44) and was statistically significant (p <0.001), the average cholesterol level in the intervention group after being given soy milk was lower (Mean= 232.94; SD= 7.56) compared to before the intervention (Mean= 261.24; SD= 13.27) and was statistically significant (p <0.001). Conclusion: Soy milk is effective in lowering systolic and diastolic blood pressure and cholesterol levels in women of childbearing age.

The predicted variation of blood pressure and plasma lipid levels, based on association with body weight, age, cigarette smoking and oral contraceptive usage, was examined in 47 000 self-referred subjects who attended a community programme for coronary risk factor screening. In both sexes, blood pressure and plasma lipid (cholesterol and triglyceride) levels were positively correlated with age and body mass index (BMI, kg/m2). Plasma triglyceride concentrations were positively correlated with cigarette smoking. Partial correlation analysis showed age and BMI to be independently correlated with blood pressure and plasma lipids. Plasma cholesterol and triglyceride levels were correlated with each other independently of the effects of age and BMI. Multiple regression analysis showed age to be a more powerful predictor of blood pressure and plasma lipid levels in females than in males, while BMI was a more powerful predictor of blood pressure and plasma lipid levels in males than in females. Current cigarette smoking did not contribute to the prediction of blood pressure or plasma cholesterol level in either sex, but did predict a 10% higher plasma triglyceride level in both sexes. Oral contraceptive usage did not contribute to the prediction of plasma cholesterol level in multiple regression analysis, but did predict higher plasma triglyceride and blood pressure levels. In view of the high prevalence of overweight people in the Australian community, weight reduction would probably be associated with a significant fall in the risk of coronary heart disease, particularly in males.

Half of all adult deaths (and much severe disability) are caused by cardiovascular diseases, and most of these deaths involve ischemic heart disease or stroke. The Asia-Pacific region accounts for about half of the global burden of cardiovascular disease and the proportion is likely to increase during the next few decades.1,2 Smoking and elevated levels of systolic blood pressure (SBP) and total blood cholesterol are major causes of cardiovascular disease,3 yet much of our knowledge about the associations between these risk factors and cardiovascular diseases comes from studies carried out in North American and western European countries. In most Asian countries, however, the mean levels of total cholesterol are lower than those found in Western countries and the incidence of coronary heart disease (CHD) is also lower, whereas the incidence of stroke, particularly hemorrhagic stroke, is higher. Article p 3384 The Asia Pacific Cohort Studies Collaboration report in this issue of Circulation investigates the combined effects of SBP and total cholesterol on risk of cardiovascular disease in a meta-analysis of 36 cohort studies (29 conducted in Asia and 7 from Australia and New Zealand) involving 380 000 individuals.4 This meta-analysis differs from previous studies in several ways: It is the largest study from this region, involving >3000 CHD events and 4000 stroke events; individual records were available for each of the participants in each study, with cause and age of death (if applicable); and information on several thousand repeat measurements of blood pressure and cholesterol made during prolonged follow-up allowed correction for “regression dilution.” These features …

We examined factors predicting knowledge of one's blood pressure, total cholesterol, and high-density lipoprotein levels (HDL) among older persons who reported a recent blood pressure or cholesterol test. Data come from a self-administered, health risk assessment that was mailed to health plan members, age 55 and older, in a Santa Barbara, California medical group. Despite their universal access to health care and high levels of reported compliance with preventive health care screening practices, 41%, 49%, and 77% of respondents reported that they did not know their blood pressure, cholesterol, or HDL levels, respectively. After controlling for potential confounders, age and low income were inversely associated with the respondents' ability to report each level. In addition, current smoking and obesity were inversely associated with self-reported knowledge of both cholesterol measures. Persons taking medication for hypertension or hypercholesterolemia were much more likely than those not taking medication to be able to report their blood pressure and cholesterol levels. Except for persons currently undergoing treatment for related conditions, these results suggest that a substantial proportion of the older persons at high risk for cardiovascular disease do not know their levels of these important biological risk factors. This lack of knowledge has important implications for public health education, and may hinder risk-reduction efforts among the elderly.

Daily activities and occupation can significantly influence health conditions, so a health assessment related to occupational factors is essential to reduce the risk of the disease. One of the leading causes of mortality from cardiovascular disease worldwide is hypertension. This study aims to determine the correlation between the type of occupation toward blood pressure and cholesterol levels in individuals with hypertension. This paper was an analytical observational study with a cross-sectional approach. The population was individuals with hypertension at Depok 2 Public Health Centre, Sleman Regency, Special Region of Yogyakarta. In addition, the sample was 121 respondents with consecutive sampling. The independent variable was the type of occupation, and the dependent variables were blood pressure and cholesterol levels. Instruments were a questionnaire to evaluate the characteristics of respondents and the type of occupation, a digital sphygmomanometer to examine blood pressure, and cholesterol test kits to assess cholesterol levels. The data analysis used the Chi-Square test with α=0.05. Most respondents were female (59.5%) and aged 60-69 years old (47.1%). They worked in the informal sector (81.2%). In addition, they had grade 1 hypertension (52.1%). There was no significant correlation between the type of occupation and blood pressure in individuals with hypertension (p=0.248). In addition, most respondents had high cholesterol levels (50.4%). Furthermore, there was no significant association between the type of occupation and cholesterol levels in individuals with hypertension (p=0.128). In conclusion, the type of occupation is not a risk factor for increased blood pressure and cholesterol levels in individuals with hypertension.

The present study was conducted to test the association between protein intake and blood pressure, glucose levels, and blood cholesterol in a large sample of Italian older adults. Longevity Check-up 7+ (Lookup 7+) is an ongoing project that started in June 2015. The project is conducted in unconventional settings (e.g., exhibitions, malls, health promotion campaigns) across Italy with the aim of fostering adoption of healthy lifestyles in the general population. For the present study, participants were eligible if they were 65+ years and provided written informed consent. Systolic (SBP) and diastolic blood pressure (DBP), and blood glucose and cholesterol levels were assessed. Protein intake was estimated using a 12-item food frequency questionnaire. Three-thousand four-hundred and four older adults were included in the study. The results of the linear regression showed an inverse association between protein intake (as a continuous variable) and DBP, and a positive correlation with blood cholesterol levels. The findings of the present study indicate that a high intake of protein was negatively associated with DBP and positively associated with total blood cholesterol levels in a large cohort of Italian older adults, after adjustment for numerous covariates.

The extent to which moderate overweight (body mass index [BMI], 25.0-29.9 [calculated as weight in kilograms divided by height in meters squared]) and obesity (BMI, >/= 30.0) are associated with increased risk of coronary heart disease (CHD) through adverse effects on blood pressure and cholesterol levels is unclear, as is the risk of CHD that remains after these mediating effects are considered. Relative risks (RRs) of CHD associated with moderate overweight and obesity with and without adjustment for blood pressure and cholesterol concentrations were calculated by the members of a collaboration of prospective cohort studies of healthy, mainly white persons and pooled by means of random-effects models (RRs for categories of BMI in 14 cohorts and for continuous BMI in 21 cohorts; total N = 302 296). A total of 18 000 CHD events occurred during follow-up. The age-, sex-, physical activity-, and smoking-adjusted RRs (95% confidence intervals) for moderate overweight and obesity compared with normal weight were 1.32 (1.24-1.40) and 1.81 (1.56-2.10), respectively. Additional adjustment for blood pressure and cholesterol levels reduced the RR to 1.17 (1.11-1.23) for moderate overweight and to 1.49 (1.32-1.67) for obesity. The RR associated with a 5-unit BMI increment was 1.29 (1.22-1.35) before and 1.16 (1.11-1.21) after adjustment for blood pressure and cholesterol levels. Adverse effects of overweight on blood pressure and cholesterol levels could account for about 45% of the increased risk of CHD. Even for moderate overweight, there is a significant increased risk of CHD independent of these traditional risk factors, although confounding (eg, by dietary factors) cannot be completely ruled out.

ObjectiveTo understand general practitioners’ (GPs) use of individual risk factors (blood pressure and cholesterol levels) versus absolute risk in cardiovascular disease (CVD) risk management decision-making.DesignRandomised experiment. Absolute risk, systolic blood...

Hypertension is a degenerative disease that is common in elderly. This can be a risk factor for stroke, heart failure, and coronary disease. One of the factors of hypertension is high cholesterol levels, lack of sports activities, and poor food consumption habits. This study aims to investigate the effectiveness of the Walking, Passion fruit and Mineral Water (JAKI-MAAP) intervention on blood pressure and cholesterol levels in the elderly with hypertension and high cholesterol. This study conducted a quasi-experimental design. This study analyzed the effect of JAKI-MAAP treatment on cholesterol levels and blood pressure levels before and after treatment. By using purposive sampling technique, the number of respondents was 15 respondents in the treatment group and 15 respondents in the control group. The results showed that there was an effect of JAKI-MAAP on the average level of cholesterol reduction in the intervention group of 32 mg/dl (p= 0.000) and the control group 10.13 mg/dl (p= 0.003). There was an effect of JAKI-MAAP on the decrease in systolic and diastolic blood pressure in the intervention group (p= 0.000) whereas in the control group showed no significant changes (p> 0.05). In conclusion, the JAKI-MAAP intervention could effectively reduce cholesterol levels and blood pressure levels of the elderly who suffered from high cholesterol and mild hypertension.

Hyperhomocyst(e)inemia is associated with premature peripheral vascular, cerebrovascular, and coronary artery disease. Because homocysteine has been found to be damaging to endothelial cells in animal and cell culture studies, we evaluated the association between hyperhomocysteinemia and arterial endothelial dysfunction (a marker of early atherosclerosis) in asymptomatic adult subjects. Using high-resolution ultrasound, we measured endothelium-dependent flow-mediated dilation (EDD) and endothelium-independent nitroglycerin-induced dilation (GTN) of the brachial artery in 14 prospectively defined hyperhomocysteinemic (mean plasma homocysteine, 34.8+/-8.5 micromol/L), nonsmoking, healthy subjects aged 53+/-9 years and 14 control subjects with low plasma homocysteine levels (9.9+/-3.2 micromol/L). The two groups were well matched for age; sex; body mass index; blood pressure, blood cholesterol, folate, and vitamin B12 levels; and vessel diameter. EDD was significantly lower in hyperhomocysteinemic subjects (6.5+/-1.7%) than in subjects with low homocysteine levels (10.8+/-1.7%) (P<.001). GTN responses were similar in the two subject groups (P=.90). Multivariate analysis confirmed homocysteine level as the strongest predictor for impaired EDD, independent of age, sex, body mass index, or blood pressure, folate, vitamin B12, and cholesterol levels. Hyperhomocysteinemia is an independent risk factor for arterial endothelial dysfunction in healthy middle-aged adults.

Effect of lifestyle modification awareness program on cardiovascular risk profile in high school students

Context: Physical activity has the potential to reduce blood pressure and cholesterol levels, but its effectiveness in gout patients has not been widely studied. Aims: To assess the effectiveness of range of motion (ROM) exercises work in lowering gout patients' blood pressure and cholesterol. Methods: This study employed a pre-experimental design with a one-group, pre- and post-test approach. The sample was 20 gout patients who were not undergoing treatment with uric acid-lowering drugs for the past two weeks. The sample received an eight-week ROM physical activity intervention. Serum uric acid, cholesterol levels, and blood pressure were measured before and after the intervention using AutoCheck 3in1 and a sphygmomanometer. Data were analyzed using the paired t-test to assess significant changes and differences before and after the intervention. Results: Significant decrease in systolic and diastolic blood pressure after being given ROM physical activity for eight consecutive weeks was observed. By week VIII, the systolic and diastolic blood pressures were significantly reduced (p&lt;0.001 for both). In addition, total cholesterol levels were significantly reduced by Week VIII (p&lt;0.001). Conclusions: This study demonstrates that ROM exercises are an effective, low-intensity intervention for reducing blood pressure and cholesterol levels in patients with gout. This form of exercise can be particularly beneficial for individuals with limited physical capacity, offering a safe and accessible option for managing cardiovascular risk factors associated with gout. Future research should explore long-term effects and potential mechanisms underlying these improvements.