Abstract
: Evidence on the effectiveness and safety of acupuncture for cerebral palsy (CP) is inconsistent, and methodological quality has not been comprehensively assessed in systematic reviews (SRs) or meta-analyses (MAs). This overview aims to integrate the evidence from SRs, summarize the safety issues, and comprehensively assess the methodological quality. : 11 databases were searched for SRs/MAs. Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2) was used to evaluate the methodological quality of the included SRs. The quality of the reporting was determined according to The Preferred Reporting Items for Systematic Reviews and Meta-Analyses of acupuncture (PRISMA-A). Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was applied to assess the quality of evidence for the primary outcomes. Risk of Bias in Systematic Reviews (ROBIS) evaluated the risk of bias of included SRs. Network meta-analysis(NMA) for comparing the relative effectiveness of different acupuncture treatments for CP. : 9 SRs/MAs included 107 randomized controlled trials (RCTs) with 9744 patients. Evidence suggests that acupuncture can increase the total effective rate and improve motor function, independence, and activities of daily living without serious adverse events. NMA indicated that needle acupuncture showed a slight statistical difference in improving the overall effectiveness of CP. : Evidence from SRs and NMA suggests that acupuncture for CP is promising and safe. Needle acupuncture is expected to be the best treatment for CP; however, the clinical differences may not be significant. The low methodological quality and the slight overlap of SRs limit the conclusions of this overview. 1 1 1. AMSTAR-2: Assessing the Methodological Quality of Systematic Reviews 2 2. PRISMA-A: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses of acupuncture 3. GRADE: Grading of Recommendations Assessment, Development, and Evaluation 4. ROBIS: Risk of Bias in Systematic Reviews 5. CP: Cerebral palsy 6. SRs: Systematic reviews 7. MAs: Meta-analysis 8. SCPE: The Surveillance of Cerebral Palsy in Europe 9. RCTs: Randomized controlled trials 10. EBM: Evidence-based medicine 11. GMFM: Gross Motor Function Scale 12. MAS: Modified Ashworth Scale 13. ADL: Activities of Daily Living Scale 14. CFADC: Comprehensive Function Assessment for Disabled Children 15. NMA: Network meta-analysis 16. CCA: Corrected covered area 17. IF: Inconsistency factors 18. SMD: Standardized Mean Difference 19. WMD: Weighted Mean Difference 20: OR: Odds ratio 21. RR: Relative risk 22. CI: 95% credible intervals
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
