Effective radiotherapy in rarely observed para-aortic lymph node metastases of sinonasal schwannoma-clinical case from our practice

Abstract

Schwannoma is benign neurogenic tumor, that arise from Schwann cells of the peripheral nerve sheath. Malignant schwannomas transformation is extremely rare. Histopathological and immunohistochemical analysis confirmed the final pathohistological diagnosis, which is extremely important for the assessment of the therapeutic approach. Schwannomas lymph node metastases are extremely rare and poorly characterized. We present an extremely rare sinonasal schwannoma with metastases in the para-aortic lymph nodes. More interesting is that metastatic para-aortic lymph nodes were affected by radiotherapy . In this article, we share the surprising fact, that the proved through FDG-PET/CT para -aortic lymph node metastases in sinonasal schwannoma with a limitation of more than 3 years, is effectively responded after radiotherapy with total dose over 45 Gy.