Abstract
BackgroundAfter thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions.MethodsEight beagles were divided into an experimental group (five males) and a control group (three females). The experimental group underwent thoracotomy on both the left and right sides of the chest. Both sides received the membrane, and the membrane on one side was glued to the pleura using tissue adhesive. The control group underwent thoracotomy only on the left side. Two weeks postoperatively, all dogs were sacrificed and adhesions were evaluated macroscopically and microscopically.ResultsSevere adhesion was seen between the parietal and visceral pleura in all control dogs, whereas the experimental group showed minor adhesion in only one dog on one side.ConclusionsOur novel anti-adhesive membrane appeared highly effective in preventing postthoracotomy pleural adhesions.
Highlights
Postoperative adhesions occur at a high rate following surgical operations
Our novel anti-adhesive membrane appeared highly effective in preventing postthoracotomy pleural adhesions
The use of our novel anti-adhesion membrane reduced the incidence of postthoracotomy pleural adhesions to an extremely low level, and adhesions were slight when they occurred
Summary
Postoperative adhesions occur at a high rate following surgical operations. New membrane effective for preventing postthoracotomy pleural adhesion in dogs. Adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions
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