Abstract
One of the approaches for reducing exposure to mycotoxins is to lessen their bioavailability by applying nanocomposite adsorbents. Magnetic graphene oxide (MGO) is a new class of nanostructured multifunctional nanocomposite materials, which play a vital role as an adsorbent. The primary aim of this study is to apply response surface methodology (RSM) to optimize the influence of pH within the range of 3 to 7, time (3–7 h), and temperature (30–50 °C), on the simultaneous detoxification of aflatoxin B1 (AFB1) and ochratoxin A (OTA) by using MGO. The optimal condition was obtained at pH 5, 5 h, and 40 °C. Further investigation of the adsorption evaluation was carried out by studying different parameters, such as the influence of contact time, initial mycotoxins concentration, and temperature. According to the experimental data, it can be concluded that the pseudo-second-order kinetic model and the Freundlich isotherm fitted well. The capability of adsorption for the Freundlich model was calculated as 153 and 95 ng/g for AFB1 and OTA, respectively. The thermodynamic study showed that the sorption studies act spontaneously as an exothermic process. These findings suggest that the application of MGO as a nanocomposite is of great significance for the detoxification of mycotoxins.
Highlights
Published: 2 November 2021Some filamentous fungi species are capable of producing mycotoxins, and these fungi grow under suitable physiological, biological, and chemical conditions that can be toxic and hazardous to the health of humans and animals [1]
Substantial economic losses arising from the worldwide occurrence of mycotoxins have had significant adverse impacts on crops and livestock [2]
The presence of aflatoxin B1 (AFB1) and ochratoxin A (OTA) has often been demonstrated in both poultry and cattle feed, eggs, and edible tissues [4]
Summary
Published: 2 November 2021Some filamentous fungi species are capable of producing mycotoxins, and these fungi grow under suitable physiological, biological, and chemical conditions that can be toxic and hazardous to the health of humans and animals [1]. Around 300–400 different mycotoxins have been isolated so far [1] Among these secondary metabolites, OTA and AFB1 have widely distributed feed and food contaminants that have potent health hazards for humans and animals. OTA and AFB1 have widely distributed feed and food contaminants that have potent health hazards for humans and animals These two mycotoxins are more frequently produced by Aspergillus species [3]. Once mycotoxins are secreted in feed or food, their detoxification has frequently been an immense task for both the agricultural and food industries To this end, numerous chemicals, biological, and physical techniques have been developed to reduce or eliminate these toxic compounds in polluted feed and foodstuffs [5]. As for biological methods, there is insufficient information regarding their mechanisms of action and toxicity of their transformation products [7]
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